Latest qNMR Experiments
Latest qNMR Experiments There is a rapidly growing use of NMR for quantitation (qNMR) and its extension, mixtures analysis. [1] The experiment most commonly used for the purpose is a simple 1D 1 H spectrum. Whilst this suits many purposes, there are cases where this approach is insufficient or ambiguous, often as…
Getting picky with qNMR
Getting picky with qNMR Click to see the video! John Gauvin, Assistant NMR Scientist at DSM, Netherlands, gave a free webinar about a statistical comparison made on several quantification techniques using Mnova NMR software. Abstract NMR is well known and heavily used for structural assignments, but in recen…
qNMR: the best pulse length for acquisition
qNMR: the best pulse length for acquisition I recently had the chance to catch up with qNMR “guru”, friend, and collaborator – Torsten Schönberger (BKA, Germany). After a few “Kölsch” beers, attention naturally turned to the very basic question: what is the best pulse tip angle to use for qNMR experiments? Of cou…
qGSD: Quantitative Global Spectral Deconvolution
qGSD: Quantitative Global Spectral Deconvolution Mnova has always used GSD for peak picking and integration. qGSD, new in Mnova 12, takes this to a new level when accurate integration is needed – as with qNMR. Global Spectrum Deconvolution (GSD) is a novel qNMR technique for an automatic peak analysis of NMR sp…
Edited Sum Integration for qNMR
Edited Sum Integration for qNMR Introduction qNMR is a common theme in my blogs, and it is always interesting and fun to speak with the growing number of like-minded colleagues. Dr John Gauvin (DSM, Holland) recently gave an excellent webinar presentation where he compared the errors and accuracy that can be expe…
Getting REALLY fussy about integration
Getting REALLY fussy about integration A quiet revolution is occurring in the world of quantitation: qNMR. [1] I have written extensively on the subject in this blog [2], and there are many excellent peer-reviewed articles to consider. The big attractions for analysts are speed and convenience . You do not need…
qNMR Purity Recipes Book
qNMR Purity Recipes Book 1. Sample Preparation The technique requires that you co-dissolve your analyte together with an appropriate reference material. The NMR signal for this must be collected under quite careful conditions if the experiment is to be quantitative. Finally, the spectrum must be processed and…
